COMPOSITION:
Each gm contains: Ciclosporin EP 2 mg
MODE OF ACTION:
When applied ophthalmically, ciclosporin is believed to act as a local immunomodulator of diseases suspected to be immune- mediated such as keratoconjunctivitis sicca (KCS) and chronic superficial keratitis (CSK). In the management of KCS, the mechanism by which ciclosporin causes an increase in lacrimation is poorly understood. Clinical improvement in cases of KCS is not necessarily dependent on an increase in aqueous tear production.
INDICATIONS:
Ciclosporin ophthalmic ointment is indicated for management of chronic keratoconjunctivitis sicca (KCS) and chronic superficial keratitis (CSK) in dogs.
DOSAGE AND ADMINISTRATION:
Remove debris with suitable nonirritating solutions. Apply a Y. inch strip of ointment to the affected eye(s) every 12 hours. The ointment may be placed directly on the cornea or into the conjunctival sac. It is recommended that dogs exhibiting chronic recurring conjunctivitis be tested for adequate tear production to determine if they are suffering from early stages of chronic KCS.
For best results in treating KCS, ciclosporin ophthalmic ointment should be administered early in the course of the disease before irreversible damage to the lacrimal tissue, or dense corneal scarring or pigmentation occurs.
Dogs afflicted with KCS or CSK will most likely require lifelong consistent therapy. For CSK, because environmental factors such as ultraviolet (UV) radiation are implicated in the pathogenesis, clinical signs may subside in the winter months when light intensity
is reduced or if the dog is moved to a lower altitude, or indoors, and thus exposed to less UV radiation.
In cases refractory to ciclosporin, the diagnosis should be reevaluated and a different course of therapy considered. Periodic reassessment of the need for ciclosporin ophthalmic ointment therapy is recommended.
PRESENTATION: Visiocare ointment is available in a 3.5 g tube in a carton.
STORAGE: Store below 30°C. Protect from light.
PRECAUTIONS: Use the content within one month after opening the container.
Keep out of reach of children. For external use only.
For ophthalmic use in dogs only.
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